Nasopharyngeal Colonization of Neisseria meningitidis Serogroup W135 in Healthy Turkish Recruits
Bulent Ahmet BEŞİRBELLİOĞLU, Mehmet Ali SARAÇLI, Ismail Yaşar AVCI, Abdullah KILIÇ, Can Polat EYİGÜN, Alaaddin PAHSA, Levent DOĞANCI
Özet
B AC K G R O U N D
All recruits in the Turkish army are immunized against
N ei ss er ia men i ng it id i s only serogroup A and C during
their first days of service. We investigated nasopharyngeal
colonization of N. meningitidis serogroup W135 in
twenty year-old healthy Turkish recruits.
M ET H O D S
We obt a ined nas o pharyngeal swabs from 330 recr uits at
a tt e nd a nce and a month later. We tested rec ov ered N.
m en i ng it id i s s t r ains with mon o cl onal ant is era for
serogrouping, and Rest r i ct ion Fragment Length Polym
o r phism for gen o t ypic analysis.
R E S U LT S
No strain of N. men i ng it id i s serogroup W135 was
cultured at attendance. At the end of the first month,
culture from three recruits (0.90%) yielded positive result
for N. men i ng it id i s serogroup W135. Genotypic
appearance of these three stains showed us that they had
two different genotypes, i.e. two different source.
CO N C L U S I O N S
The colonization rate of N. men i ng it id i s serogroup
W135 in this Recruit Center was too small (0.90%). We
need larger scaled surveillance studies to show the carriage
rate of N. meningitidis serogroup W135 in order to
change the content of meningococcal vaccine.
All recruits in the Turkish army are immunized against
N ei ss er ia men i ng it id i s only serogroup A and C during
their first days of service. We investigated nasopharyngeal
colonization of N. meningitidis serogroup W135 in
twenty year-old healthy Turkish recruits.
M ET H O D S
We obt a ined nas o pharyngeal swabs from 330 recr uits at
a tt e nd a nce and a month later. We tested rec ov ered N.
m en i ng it id i s s t r ains with mon o cl onal ant is era for
serogrouping, and Rest r i ct ion Fragment Length Polym
o r phism for gen o t ypic analysis.
R E S U LT S
No strain of N. men i ng it id i s serogroup W135 was
cultured at attendance. At the end of the first month,
culture from three recruits (0.90%) yielded positive result
for N. men i ng it id i s serogroup W135. Genotypic
appearance of these three stains showed us that they had
two different genotypes, i.e. two different source.
CO N C L U S I O N S
The colonization rate of N. men i ng it id i s serogroup
W135 in this Recruit Center was too small (0.90%). We
need larger scaled surveillance studies to show the carriage
rate of N. meningitidis serogroup W135 in order to
change the content of meningococcal vaccine.
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